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It is believed that the accumulation and aggregation of -synuclein is caused by its overexpression and the failure to clear the protein through proteolysis and autophagy mechanisms efficiently

Mitophagy maintains the normal number and function of mitochondria by removing damaged mitochondria

Aging can also set you up for a B12 shortage since absorption declines as you get older

Purified mouse CD45RABC extracellular domain with a C-terminal 6-His tag (accession #: NP_001104786, catalog number: 114-CD-050) was purchased from R&D systems

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